Integration of Nano- And Biotechnology for Beta-Cell and Islet Transplantation in type-1 Diabetes Treatment

Andras Dinnyes, Andrea Schnur, Suchitra Muenthaisong, Peter Bartenstein, Charles-Thibault Burcez, Neal Burton, Clemens Cyran, Pierre Gianello, Elisabeth Kemter, Gabor Nemeth, Francesco Nicotra, Eszter Prepost , Yi Qiu , Laura Russo , Andras Wirth, Eckhard Wolf, Sibylle Ziegler, Julianna Kobolak

D.O.I: 10.1111/cpr.12785

Cell Prolif . 2020 May;53(5):e12785. Cell Proliferation 2020

A decade of experience with genetically tailored pig models for diabetes and metabolic research

Silja Zettler, Simone Renner , Elisabeth Kemter, Arne Hinrichs, Nikolai Klymiuk, Mattias Backman, Evamaria Olga Riedel, Christiane Mueller, Elisabeth Streckel, Christina Braun-Reichhart, Ana Sofia Martins, Mayuko Kurome, Barbara Keßler, Valeri Zakhartchenko, Florian Flenkenthaler, Georg Josef Arnold, Thomas Fröhlich, Helmut Blum, Andreas Blutke, Rüdiger Wanke, Eckhard Wolf

D.O.I: 10.1590/1984-3143-AR2020-0064

Animal Reproduction, Brazilian College of Animal Reproduction, 2020

A New Approach for Glyco-Functionalization of Collagen-Based Biomaterials

Ines Figuereido, Alice Paiotta, Roberta Dal Magro, Francesca Tinelli, Roberta Corti, Francesca Re, Valeria Cassina, Enrico Caneva, Francesco Nicotra, Laura Russo

D.O.I: 10.3390/ijms20071747

International Journal of Molecular Sciences, Multidisciplinary Digital Publishing Institute (MDPI), 2019

Glycans in Nanomedicine

Susanna Sampaolesi, Francesco Nicotra, Laura Russo

Glycans have been selected by nature for both structural and ‘recognition’ purposes. Taking inspiration from nature, nanomedicine exploits glycans not only as structural constituents of nanoparticles and nanostructured biomaterials but also as selective interactors of such glyco-nanotools. Surface glycosylation of nanoparticles finds application in targeting specific cells, whereas recent findings give evidence that the glycan content of cell microenvironment is able to induce the cell fate. This review will highlight the role of glycans in nanomedicine, schematizing the different uses and roles in drug-delivery systems and in biomaterials for regenerative medicine.